Much remains to be done to understand the control of the expression and location of the range of variants produced by each Syt.
Furthermore, the limited coverage that can be sampled (generally <100 clones and 100 K nucleotides per population) is far from the range of variants (105 109) typically found in virus samples.
Although random sampling effect was observed, the range of the variant allele detection ratio at the polymorphic positions was narrowed as the coverage increased for both experiments (Additional file 1).
It is the aim of this chapter to describe both the basic operating elements of the decanter, and the range of design variants and special features.
We developed a method that leverages haplotypes to identify chromosomal segmental alterations in cancer and uses this information to join haplotypes together, thus extending the range of phased variants.
Quality assurance for clinical next-generation sequencing (NGS based assays is difficult given the complex methods and the range of sequence variants such assays can detect.
In order to characterize definitively the range of FGFR2 variants expressed by SUM-52PE cells, individual isoforms were cloned and sequenced from SUM-52PE RNA.
Here, we sample the range of opa variants in the inbred isofemale Raleigh (RAL) lines constituting the Drosophila melanogaster genetic reference panel (DGRP), additional classical Notch alleles, X balancers, and other informative stocks.
A single probe must, however, be very accurately designed to cover the range of splice variants feasible, and must reside in an area accessible to the RNA or DNA fragments hybridizing.
This is the first study to combine retail audit and interview data to not only explore how e-cigarettes are being promoted and trends in their availability in the UK retail setting, but also to provide a unique perspective on retailers' views on the long-term viability of the products, and how their customers are responding to the range of product variants on offer.
