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21 However, the evidence base is limited in terms of the range of trials, researchers and patients that have informed this previous work, and there has been no systematic evaluation of the extent to which trialists' intentions for PPI are put into practice.
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Each block comprised two practice trials that were randomly selected from the range of possible trials for that block; and 16 experimental trials.
All other toxicities were in the range of other trials with the exception of grade 3 or 4 lymphocytopaenia.
Nevertheless, our results compare well with many other series regarding local control and are in the range of other trials using more intensive neoadjuvant approaches with higher rates of pathological response in terms of disease-free and overall survival.
Current product registration in the USA limits the use of tigecycline to adults with intraabdominal and complicated SSSIs, but the range of clinical trials still underway indicates that the drug is expected to contribute to the treatment of patients with a much wider range of conditions caused by multiresistant pathogens.
Sample size estimates suggest that such a trial is feasible, and within the range of previously supported trials of malaria interventions, although substantial issues to implementation exist.
Our result is in the range of 2 chemotherapy trials [ 9, 20].
The range of the number of trials that were needed to find significance was four to eight.
However, the range of forces across trial types was less than 1 N.
It lists the median number (with range) of trials per participant for each of the twelve possible outcomes (see Materials & Methods).
Ship builders celebrate "keel laying" as the formal start of construction, naming, stepping the mast (accompanied by placing coins under the mast for good luck), christening (accompanied by breaking a bottle of champagne over the bow), a whole range of trials, "sail away", hand over, and my personal favorite - onboarding the new captain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com