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The diversity of solid-state forms that an active pharmaceutical ingredient (API) may attain relies on the repertoire of non-covalent interactions and molecular assemblies, the range of order, and the balance between entropy and enthalpy that defines the free energy landscape.
In addition to size differences, we found that the range of order sizes was extremely skewed with far more small than large orders.
Only 14 of the 38 orders met this requirement because the range of order sizes was extremely skewed with far more small than large orders (Table 1).
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The range of orders where the detection ratio does not increase drastically is [18, 28].
The CDF curve showed that IN is located in the range of ordered proteins.
If we use Henkin models, in which the range of second order quantifiers has more freedom, an axiomatization becomes available.
The nanoparticles of ZnO are converted to agglomerates of plate-like ZCA particles with non uniform shapes and sizes, in the range of micrometer order.
The vacuum in the range of the order of 2.0 × 10−5 mbar is regularly achieved in the chamber.
Despite the fact that the number of samples is comparatively smaller than in the case of CGH (in the range of one order of magnitude lower) the resolution of the Array-CGH was good enough to obtain significant results.
The miR-145 in human brain total RNA could be detected quantitatively in the range of seven orders of magnitude with high linearity and reproducibility.
(2) The temperatures are distributed within narrow range (ΔkT ∼ 0.08 keV) with an average temperature of 0.18 keV in spite of the range of four orders of magnitude in luminosity (1041 45 erg s−1).
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CEO of Professional Science Editing for Scientists @ prosciediting.com