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Immunolocalization allows discrimination between the range of modifications, provides a genome-wide level of analysis, allows differential assessment of nuclear localisation, and is compatible with the limited DNA available within the early embryo.
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Otherwise the range of modification depends on the quality of the BSF solution.
The initial parameter settings for the modification mass cluster centers, shared for all three algorithms, were initialized randomly within the range of modification masses in the input dataset.
Common methods of gas-jet characterization rely on measuring the effective thickness using nuclear elastic scattering and energy loss techniques; however, these tests are time intensive and limit the range of design modifications which can be explored to improve the properties of the jet as a nuclear reaction target.
However, the range of chromatin modifications regulated by Myc on its target loci remains unknown.
The range of these modifications is also strictly limited, and defines rules for allometric plasticity in the context of environmental fluctuations [22].
Furthermore, these examples demonstrate that while the range of chemical modifications possible is limited, unnatural analogs can be accepted as substrates in chemoenzymatic reactions.
The simplicity and high efficiency of this system allows its widespread use for many different applications, greatly increasing the range of genome modification experiments that can be performed.
The range of genetic modification methods employed to alter the genetic composition of microbes, plants, and animals include the targeted manipulation of genetic material and nontransgenic methods, such as chemical mutagenesis and breeding.
According to the model proposed earlier, histone modification can generally occur within a region of about 100 kbp [ 1], which is much larger than the range of co-modification observed in this study.
Radiomodulation of several regulators of chromatin condensation (RCC1) and TOM proteins that bind to viral replication proteins [113], telomere repeat factors-like AtTRFL10 and 3, and a GANP family member, which facilitates the nuclear localization of hMCM3, illustrates the broad range of modifications of DNA, histones, and non-histone proteins that occur after DNA damage.
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