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The appropriate methodology to test the effectiveness of medicines is to document the range of effects correlated with new treatments.
The report also found that "except for the harms associated with smoking, the adverse effects of marijuana use are within the range of effects tolerated for other medications".
The range of effects on patients' quality of life is a big unknown — and the reason the F.D.A. held a public hearing on Friday.
A couple of impressionistic self-portraits show the range of effects, from low-key to luminous, that give pastel its sensual appeal.
A number of speed parameters were developed to encapsulate the range of effects of the treatments.
The mysterious tonal subtleties of evening, as in Lawson's "Night Scene, Long Island," and the delicate morning glow of Dove's "Sunrise (Centerport Harbor)," represent the range of effects found in the show as a whole.
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Furthermore, it shows the range of effect size that can still be detected with small animal PET without being lost in evitable variability.
They can fit the observed data-points well (and may perform well within the range of effect sizes observed).
For example, for Crohn's disease, Park et al. estimated the number of loci to be ∼150 within the range of effect sizes of known loci while our estimate is around a thousand (as detailed in later sections).
However, the problem addressed in this study is not exactly the same as in Park et al. We are considering the entire range of effect sizes while in Park et al the range of effect sizes is limited to those observed for known susceptibility variants.
Our effect sizes (r −0.16 and −0.19) compare favourably with those typically reported for heterozygosity-fitness associations (mean r>0.10) [1], and are consistent with the range of effect sizes normally reported in evolutionary and ecological research (r's between 0.18 0.19) [83].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com