Exact(17)
The analysis plan was drawn up after the protocol was written (before analysis) to be comparable to other IPTi trials; see Analysis Plan S1 and Protocol S1.
The Cochrane Handbook acknowledges that review authors should be alert to the possibility that the importance of an outcome may only become known after the protocol was written or the analysis was carried out, and should take appropriate actions to include these in the review.
The protocol was written by the principal investigator and sponsor.
During this meeting the first draft of the protocol was written which was then extensively reviewed by technical experts.
A detailed step-by-step intervention protocol and guide for the use of the protocol was written.
At the time the protocol was written the standard treatment options for metastatic pancreatic cancer were gemcitabine and 5FU.
Similar(43)
The protocol is written down in the Handbook CQI development[ 11].
If the protocol is written as we propose in this manuscript, the maximum acceptable risk and inconvenience to participants are clearly confined within a protocol's adaptive specifications.
The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-244X/10/16/prepub The original concept of the study and the first drafts of the protocol were written by late professor Dag Neckelmann.
Our standard of care at the time this protocol was written was to use non-pharmacological interventions including swaddling and non-nutritive sucking for painful procedures, such as venipuncture and heel pricks.
The study protocol was written according to the final recommendations of the Société de Réanimation de Langue Francaise's consensus conference on weaning.
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