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Genes found to be differentially expressed between normal colon, adenoma, and carcinoma can be used as markers of the progression process.
Many inflammatory factors, including cells, cytokines and chemokines, may divergently regulate the progression process.
Loss of chromosome 8p11 may play a role in the progression process.
The fact that the log2 ratio average of aberrant regions reflects the ratio of tumors can help us follow the progression process of tumor cells [ 6].
To study the progression process, time schemes have been proposed for studying the process of colorectal cancer based on extensive clinical investigations.
Recent technological advances in genetics and epigenetics offer a better understanding of the underlying epigenetic alterations during initiation and in the progression process of the human tumors.
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To determine the relative contribution of the epithelium and the stroma to the tumor progression process, tumor pieces from p190B+/+Neu tumors and from p190B+/-Neu tumors were transplanted into cleared fatpads of SCID/beige mice.
When performing a simulation study, we should examine the event generation process, which might be suited to the situation of the disease progression process [ 22].
For instance, as these multivariate longitudinal data are actually temporal realizations of an underlying disease progression in different dimensions, how to leverage our knowledge of the disease progression process to fuse the data is a challenge.
To determine which model is the most suitable for analyzing MS clinical trial data, we conducted the simulation study with consideration of the disease progression process or natural history.
Thus, the early diagnosis of GA is crucial for slowing down the malignant progression process of gastric mucosa.
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