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The progression involves alterations in tissue organization and morphology but low genetic changes [ 1].
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The pathogenic progression involves glial activation and TLR2 signalings stimulated by LTA, which are linked to inflammatory neurodegeneration [ 82].
In the BT4C glioma, tumour progression involves changes in the overall protein expression profile, as shown in this study.
The control circuitry that directs and paces Caulobacter cell cycle progression involves the entire cell operating as an integrated system.
Disease progression involves the immune system, extracellular matrix (ECM) deposition and the microvasculature [ 1].
Mammalian cell cycle progression involves the activities of cyclins and cdks.
Tumor progression involves the transition of normal cells into malignant cells through a series of cumulative alterations.
The paper by Tan and Yan, proposes a new stochastic model of colon cancer progression, involving the chromosomal instability pathway and the micro-satellite instability pathway.
Importantly, copy-number changes at these BRCA2-linked networking regions coincide with those associated with advanced progression, involving the capacity to metastasize to the nodes or more-distant sites at diagnosis.
The major mechanisms by which HPV contribute to neoplastic initiation and progression involve the activity of two viral oncoproteins, E6 and E7, which interfere with the critical cell cycle tumor suppressive proteins p53 and retinoblastoma (Rb).
I have offered an immunity-based model to explain ovarian cancer pathogenesis and progression involving the mucin (MUC) family of glycoproteins.
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