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Exact(21)
The process of mutation, which generates genetic variation, is random, but selection is non-random.
The process of mutation provides each generation with many new genetic variations.
Once the cell has been transformed, the process of mutation does not end.
The allelic variations that make evolution possible are generated by the process of mutation, but new mutations change gene frequencies very slowly, because mutation rates are low.
Thus far, oncogenic viruses have not been shown to induce DNA mutations directly in human cells; rather, their contribution seems to lie in promoting and hastening the process of mutation.
Furthermore, in the process of mutation, unfeasible solutions are brought about.
Similar(39)
His grand theory of adaptive evolution, which is called the Shifting Balance Theory, included the processes of mutation, random genetic drift, migration, and two kinds of natural selection; natural selection acting between individuals within local populations or demes to increase individual fitness and natural selection acting among local demes to increase average individual fitness.
The processes of mutation and selection are integral to the evolution of cancer at every step of multistage carcinogenesis, from tumor genesis to metastasis.
Comparative genomics can inform us about the processes of mutation and selection across diverse taxa.
This analysis has identified the mutational pathway leading from non-toxic to highly toxic PLA2 enzymes, reconstructing the processes of mutation and adaptation.
This affects the opportunity for observing a somatic mutation and as such the reported spectrum can be a reflection of the processes of selection and/or the nucleotide architecture of the TP53 gene in addition to the processes of mutation [ 21,22].
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