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Thus, the establishment of human WT in immunodeficient mice selected and expanded a more aggressively malignant phenotype, reminiscent of the process of aggressive disease and relapse in patients.
Alternatively, it may represent important differences in the process of aggressive early metastasis (as cell line injection models represent) and slower metastatic evolution, where tumour cells proceed through a phase of latency or micrometastasis.
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Puig's agent, Jaime Torres, said his client has retained a lawyer who is in the process of filing an "aggressive" response.
Besides, hives maintained by beekeepers are less dangerous than wild hives; beekeepers effectively tame hives through re-queening — the process of removing an aggressive queen and manually adding a docile queen.
He said the Pentagon was "beginning a process of aggressive management" to try to head off some of the worst problems.
As the uPA system is frequently associated with the process of invasion/metastasis and a more aggressive phenotype in a great variety of cancers, there is a great interest in PET imaging using uPAR-directed tracers to visualise the tumour's potential for metastasis formation.
On the sofa beside us, two men have taken to aiding the process of a rather loud and aggressive blowjob by holding the woman's hair and spanking her.
The report presents a critical link between the EMT-related miRNAs miR-221 and miR-222 and the process of EMT and metastasis in aggressive breast cancers.
We suggest that selection on genetic variation in the mGlu III receptors might have played a critical role in the process of domestication that converts anxiety-associated aggressive behaviors of wild population to tame behaviors for the adaptation to the community.
While not yet demonstrated in the clinical setting, several murine xenograft studies have suggested that VEGFR inhibitors can promote a more aggressive phenotype through the process of metastatic conditioning [ 34– 34].
The aggressive policies that they are following, however, could jeopardise the process of adjustment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com