Although the frequency of mutations and the discovery of hotspot heterozygous mutations strongly argue for the importance of PIK3CA in the carcinogenic process, functional analysis of these mutations has also been performed to confirm this supposition.
Particular emphasis was placed on sequences serving under the 'biological process' functional category.
In the disablement process, functional limitations immediately precede activity limitations [ 15].
Genome-wide functional analysis of duplicate genes is in attempt to reveal functional correlation between genetic and epigenetic factors during the process of functional innovation through gene duplication.
Our study shows the ancestral function of SIG1 and the process of functional partitioning (subfunctionalization) of sigma factors during the evolution of land plants.
There are a number of other complexities that arise during the process of functional verification.
For the application of the process for functional components, it is required that the process parts perform well in cyclic applications as well.
Both processes are intimately connected and equally pivotal in the process of functional messenger RNA production.
Despite our inability to reconstruct these processes, there is evidence for individual steps in the process of functional reorganization.
