Sentence examples for the problem of specificity from inspiring English sources

Most of techniques dealing with the stated problem reduce the problem of specificity prediction to the identification of alignment positions that may be important for protein specificity.

Some base fingers in the respective grooves might be possible but without other interactions it might be hard to resolve the problem of specificity.

Most protocols still face the problems of specificity despite a major effort being made to solve this issue.

These assays, referred as interferon (IFN -γ release assays (IFN -γ, have been specifically designed to overeleasehe problem of low specificity of the tuberculin skin test (TST).

The evidence presented suggests that yeasts may be a powerful model for the screening/development of PCD-directed drugs, overcoming the problem of cellular specificity in the design of antitumour drugs, but also enabling the design of efficient antifungal drugs, targeted to fungal-specific apoptotic regulators that do not have major consequences for human cells.

This should, however, be balanced against the problem of low specificity of symptoms and the risk of overwhelming GPs.

Authors' response: The problem of cell/tissue specificity of gene sets is indeed important.

The use of human cells or tissues in the study of the effects of glucocorticoids has a distinct advantage, as it avoids the problem of species specificity.

Although these statistics provide good feedback regarding multiple aspects of a predictor's performance, they do not always address node dependency or the problem of unequal specificity of functional annotations found at the same depth of the graph.

Nevertheless, initial studies have addressed the problem of tumour specificity by showing that some of the genes mutated in large-scale breast and colorectal cancer studies are not mutated in glioblastoma, melanoma and pancreatic carcinoma (Balakrishnan et al, 2007).

While human cellular test systems would overcome the problem of species specificity, in vitro cultured human immortalized cell lines do not represent normal cell types, and human primary cells cultured in vitro usually loose their tissue-specific functions.