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It has been estimated that the probability of activating a given gene from a single integration event is >10−5 [11].
This observation suggested that the amount of DNA damage in each cell determines the probability of activating a p53 response.
In particular, forward inference denotes the probability of activating the anterior (vs posterior) cluster given the respective BD or PC.
On the other hand, by assuming that the probability of activating a molecule remains constant over time, a relationship between the cumulative number of localizations and the imaging time was found (Gunzenhäuser et al. 2012).
The lack of correlation between the rates of repair and the probability of activating p53 post damage indicates independence of the p53 response from the efficiency of the repair machinery.
We also show that the natural variations in the initial amount of p53, rate of DSB repair and cell cycle phase do not affect the probability of activating p53 in response to DNA damage.
Similar(53)
Therefore, if the total probability of the traffic exceeding the link capacity increases, the probability of GSSMS activating a Spine switch increases.
On the other hand, increasing the stimulus amplitude through needle electrodes leads to a higher probability of activating A β fibers (Mouraux et al., 2010).
Sex had no influence on the probability of being activated on the waiting list.
We therefore examined whether being inside a phosphosite cluster affects the probability of being activated by the same kinase (Table 3, additional file 2).
We identified significant effects of centre for the probability of being activated on the waiting list (fig 1) (change in −2LogL=89.9, df=1, P<0.001) and the probabilities of receiving a renal transplant from a donor after brain stem death (fig 2) (change in −2LogL=15.1, df=1, P<0.001) or a donor after cardiac death/living kidney donor (fig 3) (change in −2LogL=46.1, df=1, P=0.001).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com