Sentence examples for the primordial function of the from inspiring English sources
Particularly, the cell biology and pathobiochemistry of intestinal disaccharidases has occupied a major part of this workshop by virtue of the primordial function of the sucrase-isomaltase enzyme complex in carbohydrate and human starch digestion to glucose (α-glucogenesis) [1].
This particular function is ubiquitous across the jawed vertebrates and is likely the primordial function of the class I protein.
They use this model to propose a pathway for the addition of amino acids to the genetic code, linking the model to Szathmary's Coding Coenzyme Hypothesis (the idea that the primordial function of the (anti codon-amino anti codon-amino to deliver acido acids as coenzymes for ribozymes, and that this system was linkageo-opted for translation).
Evolutionary conservation analysis of these binding sites is greater when adjacent to up-regulated genes than down-regulated genes, suggesting the primordial function of PPARγ/RXR is in the induction of genes.
When coupled with the observation that the evolutionary conservation of PPARγ/RXR binding sites is greater when adjacent to upregulated genes than downregulated genes suggest that the primordial function of PPARγ/RXR is the induction of genes involved in lipid and fatty acid metabolism.
Human CLN3 can complement the function of the yeast gene Btn1, suggesting that the primordial function of CLN3 is sufficiently conserved to make studies in yeast relevant to the human disease.
Promoting resolution of sister DNA molecules might thus be the primordial function of SMC-kleisin complexes, which has been evolutionarily maintained in prokaryotic condensin, as well as condensin in eukaryotes.
The primordial function of autophagy has long been recognised, but its significance in multiple cellular roles and various pathological conditions, including cancer, is only now being revealed (Gozuacik and Kimchi, 2007; Lerena et al, 2008; Mizushima et al, 2008).
This point, which is of chief importance to understand the primordial function of VSGs, requires further investigation on diverse aspects such as assessing the level of exposure to the immune system of T. vivax invariant surface proteins or determining their efficiency in antibody clearing and the VSG switching rate.
Previous studies have demonstrated that expression of human CLN3 in this yeast model functionally complement an absence of Btn1p (Pearce and Sherman, 1998; Kim et al., 2003) indicating that the primordial function of CLN3 is conserved in yeast and that findings from this model will certainly provides clues about the cellular consequences of not having this protein present.
For example, there are several lines of evidence to suggest that the RAG1 and RAG2 genes involved in V(D J recombination originated from a hAT DNA transposon that was domesticated to fulfill this primordial function of the adaptive immune system [19], [20].
