At airports, passengers go through the primary screening checkpoint, and some are selected for secondary screening, which includes a baggage search and some kind of body search, like a pat-down.
Security lines moved briskly yesterday morning, and travelers expecting the requisite madness seemed surprised as they approached the airport's two primary checkpoints.
Checkpoint kinase-1 is thought to be the primary S-phase checkpoint kinase, with Chk2 playing a supportive role.
While comprehensive proof of senescence-induced senescence in tissues awaits the analysis of a senescence reporter system in vivo, our data already indicate that senescent cells induce a bystander effect that spreads DNA damage and, ultimately, induces cell senescence in primary, checkpoint-competent cells in vitro and, possibly, in vivo.
Petitioners propose several ways in which the narcotics-detection purpose of the instant checkpoint program may instead resemble the primary purposes of the checkpoints in [Michigan v.] Sitz (1990) and [United States v.] Martinez-Fuerte (1976).
Of course, there are circumstances that may justify a law enforcement checkpoint where the primary purpose would otherwise, but for some emergency, relate to ordinary crime control.
Finally, Tatiana Tatusova presented the results of NCBI's on-going annotation workshops that include experts in prokaryotic, viral, and fungal genomes, to set community-accepted annotation standards that can be used as validation checkpoints by the primary archives.
On one side, repair factors help to recruit checkpoint proteins at the damage sites onto DNA and, by modifying the primary lesions to RPA-covered ssDNA, trigger the checkpoint cascade; on the other side, once activated the checkpoint pathway stimulates the repair process mainly through direct protein protein interactions or post-translational modifications.
Because the primary purpose of the Indianapolis narcotics checkpoint program is to uncover evidence of ordinary criminal wrongdoing, the program contravenes the Fourth Amendment.
It is interesting to note that subregions 1 and 3 are analogous to subregions of human RPA2 (Table 3) that contain all but one (T21) of the primary DNA-damage-specific targets of checkpoint kinases (Anantha et al. 2007; Liu et al. 2012).
