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The number of inbred lines genotyped can be found in Supplementary Table 1 and sample size details per SNP in Supplementary Table 2. Genetic diversity among inbred lines was estimated with the previously ascertained SNPs from the study of Chelo and Teotonio (2013).
3D reconstructions of the histological volumes were computed using the following three datasets: (i) the previously ascertained 3D-MRI scan, (ii) images of the paraffin block face obtained during sectioning for the precise alignment of the histological sections and (iii) the digitized images of the cell body-stained sections (Amunts et al. 2004).
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Our data have shown that uptake of tamoxifen in a consecutive series of premenopausal women was similar to that previously ascertained in a randomised controlled trial (IBIS-I).
Taken together, these observations support the genetic discontinuity observed between Northwest Africans and their closest European neighbors [23], [36], and the usefulness of previously ascertained EuroAIMs to recover the genetic ancestry of Northwest Africans and Europeans.
Additionally, they provide the two ingredients necessary for mapping gene expression traits to genotype, at moderate cost and without the requirement for previously ascertained genetic variants.
Validation of large deletions using sequence data derived for the SHR/OlaIpcv strain and the above algorithms was previously ascertained at greater than 90% (Atanur et al., 2010 ).
NIOSH had previously ascertained the vital status of the cohort as of 31 December 1988 using the Social Security Administration, the Internal Revenue Service, post office cards mailed to the last known address, the Department of Veterans Affairs, the Health Care Finance Administration, and the National Death Index (Ward et al. 1992).
One advantage is that the potential for ascertainment biases both from surveying previously ascertained SNPs (Clark et al. 2005) and from sampling limited genomic regions (Mousset and Derome 2004) is greatly reduced.
Sometimes they said that, sometimes they didn't, depending on what they had previously ascertained about the presence of other Polish people in a locality.
Five of the 7 patients that were previously ascertained by serology and RT-PCR as having loss of A or B antigens were methylated at the ABO locus when analyzed by MS-SSCA and COBRA (patients with S prefixes, Table 3).
For these enzymes the absence of restriction sites in the 3' genomic flanking sequence had been previously ascertained.
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