The previous implication had been they did not know until Ensign's June 16 news conference.
Given the previous implication of PDR transporters in phospholipid and ergosterol metabolism, the role of Pdr18 in yeast plasma membrane lipid composition was studied.
The above results together with the previous implication of the yeast homologue of Nol9, Grc3, in rRNA maturation (Peng et al, 2003) strongly suggested a role for Nol9 in the processing of human rRNA.
The previous implication of base excision repair processes in germ line reprogramming [ 43, 46], which by itself would pose a tremendous risk for maintenance of genome integrity if operative at a global level, may have various other explanations.
Given the previous implication of ferritin and other iron-binding proteins (that is, transferrin and hepcidin) in SLE, we pursued this increase further to gauge its clinical significance and possible mechanistic origins.
Therefore, PDCD4 and HSP27, which have previous implications in regulation of apoptosis and carcinogenesis, may represent potential therapeutic targets for treatment of CLL.
One miRNA without previous implications in ccRCC is miR-3065-5p, antisensense miRNA to miR-338 [ 53].
This result supports the previous experimental implication that the possession of a single hydroxyl group is sufficient for the inhibitory activity of 1,4-naphthoquinone inhibitors.
The crucial role SLC1A2 has in the uptake of the glutamate from the synaptic cleft and the previous genetic implication of the gene in BD suggests that this gene represents a potentially interesting gene to be studied in our BD and SZ cohorts.
Barrett et al. [ 6] and McGovern et al. [ 8] highlighted ORMDL3 in relation to CD and IBD, respectively, based either on a correlation between genotype and gene expression in lymphoblastoid cell lines [ 7] or on the biological role and previous implication of ORMDL3 in diseases involving dysregulated immune responses.
