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The present study still demonstrates that Yunzhi polysaccharides affects osteoblast cell growth in a dose-dependent manner by stimulating ALP activity.
Finally, the present study still has a potential limitation.
The present study still observed remnants of BCP after 9 and 12 months which suggests that the ossification rate is not the same as the resorption rate of the BCP.
Although the present study still needs to be supported by experimental data, our approach may provide new perspectives on collective immunity against 2009 H1N1 and an insight into future antigenic changes of this new human pandemic influenza virus.
However, the present study still has limitations.
A few limitations in the present study still exist.
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We are aware that our present study still has certain limitations such as the potential emotional influence.
30 Our present study still has some limitations.
Limitation of present study still remains small number of subjects caused by strict criteria used to select patients.
However, the haematological toxicity of the present study is still favourable and well tolerated with grade 3 4 neutropenia and febrile neutropenia of 7.1 and 0.9%, respectively, in a total of 323 cycles given.
One should, however, realise that the subjects of the present study were still rather young (i.e. 36 years), and that a longer exposure to lower IGF-I bioactivity might be necessary to induce unfavourable levels of risk factors for CVD and/or T2DM.
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