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Results obtained from the present model will provide a comprehensive understanding of design parameter effects and consequently improve the design/performance in a PEM electrolyzer cell.
Results obtained from the present model will provide a deep understanding of the functions of TT-LGDL morphology, and also help to optimize the design and fabrication of both the TT-LGDLs and CLs.
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Our group continues to develop and validate ovine-specific tests [17, 58], and the presented model will provide a platform to further investigate cytokine expression after BD in future studies.
Thus the results provided by the present model will be worse than what would be observed in reality.
We hope that the present model will be helpful for scientists who focus on J-proteins and will provide novel insights into the research of cell death.
The present model will specifically be developed for rats since this animal species has historically provided much of the data in the field of the hydromineral homeostasis.
Testing these models will provide the true effect directions.
The creation of a Tsc1 flox/ko ;hGFAP-Cre is in progress and will allow a comparison with the present model to provide a possible biologic basis for the differences in severity between patients with TSC1 versus TSC2 mutations.
Importantly, the LSD1 −/− model described in the present study will provide an excellent platform, which should allow the definition of the specific roles of LSD1 in tumour formation, aid in the discovery of new LSD1 inhibitors, and define the on-target and off-target effects of potential LSD1 inhibitors.
The present study will provide concrete illustration of the direct and residual QSAR models and their interpretation towards assessing a molecular mechanism for the observed genotoxic carcinogenesis, in accordance with OECD principles.
However, the present model provides an extension of previous models on three counts.
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