Sentence examples for the predominant function from inspiring English sources

Lineage-specific transitions of this kind could alter the conformational ensemble accessible to the same protein in different species, causing a functional change, even if the predominant function remains conserved.

Our data also suggest that the predominant function of ubqn is to regulate APP levels, not γ-secretase activity.

Here we consider the predominant function of 51a and 51b to be retraction of the occipital processes, with secondary adduction action.

On the other hand, the predominant function of IL-27 is anti-inflammatory (e.g., inhibition of Th2, Th17, and late-stage Th1 responses, as well as of macrophages and NK cells [38]), suggesting that the upregulation of IL-27 may constitute one of the negative feedback mechanisms which are commonly initiated in response to inflammation.

To determine the predominant function of the genes which were classified into two or more GO categories, we classed each gene according to its molecular function (nuclear receptor, transcription factor, cellular signaling and undefined) and calculated the percentage of each molecular function for each overlapped group.

The predominant function of saposin B was in sulfatide degradation.

Our finding that γ-secretase enzymatic activity correlates specifically with the level of PS2 expression suggests the novel hypothesis that PS2 is the predominant functioning γ-secretase in microglia.

The predominant functions are listed on the right of the graphs.

Interestingly, little overlap between binding regions was observed in ECCs, limb buds, and PNST cells, although the predominant functions of Twist1 occupied genes, including cell adhesion and migration are similar in the three tissues.

The genes in enriched functional categories (56 out of the 96) are shown in Additional file 4. Overall, the predominant functions were related to RNA-metabolism (i. e. RNA binding, mRNA processing, regulation of transcription, zinc ion binding) and protein folding and degradation.

Among the 216 shared genes from the chromosomal unique set, the predominant functions were related to recombination; 17 and 7 genes were predicted to encode transposases and resolvases, respectively.> Although many genes had been exchanged between plasmids and chromosomes, most of them had different promoters and terminators.