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So far, four different synthesis procedures of [11C]erlotinib have been published employing different solvents (DMF or CH3CN), reaction temperatures (80 °C or 120 °C) and bases (NaH and TBAH) for the deprotonation of the alcohol functionality of the precursor (Table 2).
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Tandem mass spectrometry analysis identified 3 nucleotide precursors ending in d-alanyl d-alanine (UDP-MurNAc-pentapeptide), d-alanyl d-lactate (UDP-MurNAc-pentadepsipeptide), and d-Ala (UDP-MurNAc-tetrapeptide). Upon induction with vancomycin, UDP-MurNAc-pentapeptide was not detected, and UDP-MurNAc-pentadepsipeptide accounted for most of the precursors (Table 2).
We identified 248 miRNA precursors with at least 10 reads that support the presence of a mature miRNA derived from the hairpin precursor (Table 2 and File S2).
Reasoning that the electronic properties of the olefin substrate could influence aziridination as well, we tested the activity of P411BM3-CIS-T438S toward the electron-rich 4-methoxystyrene using tosyl azide (TsN3) as the nitrene precursor (Table 1).
Moreover, these four variants showed specific binding to the recombinant EtSAG1 precursor (Table 3; Figure 3a).
To avoid contamination from maternal macronuclear DNA that has not been fully degraded, the sequence and/or orientation of most S. lemnae primer-pairs (Methods S1 and Figure S1) cannot amplify the fully-rearranged product, although they can amplify the unprocessed or partially processed micronuclear precursor (Table S1).
Here we added a symbol "'" after miRNA to represent the antisense of a known miRNA precursor (Table 2), i.e. hsa-mir-103 and mir-103′instead of mir-103a, b, respectively.
The chemical compositions of the prepared solids are related to the Pb/(Pb + Ca) molar ratios in the precursor solutions (Table 1).
In addition to the dsRNA-seq data, sRNA-seq data of nrpd1, rdr2 and rdr6 should also be valuable to investigate the biogenesis pathways of the sRNA precursors (Table 3).
The mean crystallite sizes of the doped-TiO2 are slightly smaller than that of its precursor (Table 1).
It was found that pore size distributions for the porous CER-based films under investigation were in the range of ~20 180 nm (Fig. 9b) and their average pore diameters were around 45 60 nm, depending on the initial IL content in the CER precursors (Table 1).
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