This review provides an overview of the plausible interactions of the outer mitochondrial membrane Voltage Dependent Anion Channel, Bcl-2 family proteins and JNKs in cytochrome c release in the peripheral ischemic stroke associated apoptotic neurons.
Molecular docking is an important computational tool to predict the plausible interactions between the drug and protein in a non-covalent fashion.
Multifactor dimensionality reduction (MDR) is an brute-force method for identifying the most plausible interactions which fit the data [ 17].
The Gcs1p protein contains the di-lysine motif and also acts as a mediator in the secretory pathway thereby suggesting a plausible interaction between the two proteins.
However, our results do suggest specific, biologically plausible, gene medication interactions, and we recommend confirmation of the biologically plausible interactions as a priority, including those for drug transporters, metabolizers, and targets of action.
Analysis of two state-specific cigarette tax increases in Florida and New York largely corroborated the SCHIP trends and suggest plausible interaction between tax increases across geographies.
In addition to suggesting a possible role for Gsn in the regulation of embryonic mammary epithelial morphogenesis, the network analysis identifies connections to plausible interaction partners since both CXCR4 and CXCL12/SDF have well-established roles in invasive cell behaviour.
This model was checked for collinearity and interaction between variables by incorporating biologically plausible interaction terms in the model.
Finally, some biologically plausible interaction effects among the sociodemographic variables (sex, age, and solitary living) and cognitive and functional abilities at baseline were included in the analysis.
Finally, the regulation factor that predicts an expression pattern with highest correlation to the observed expression pattern is identified as most plausible interaction form that TFs take to regulate this target gene.
