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The changes in Ca2+ homeostasis may be related to the rapid muscular contraction and consequent paralysis in the parasite due to the anthelmintic stress caused by the phytochemicals of F. vestita.
Olajuyigbe et al. (2011) studied the phytochemicals of Waltheria americana root, stem, and leaf extracts and reported that it contained alkaloids, anthraquinones, cardiac glycosides, phenols, tannins, and saponins.
The reason associated with hypnotic activity might be due to binding with the phytochemicals of used plant in NKB to benzodiazepines receptors (BZ1, BZ2 and BZ3) to exhibit anxiolytic, hypnotic, lean muscle relaxation and anticonvulsant [ 47].
We assume that the phytochemicals of AP are responsible for the down regulation of the pro-inflammatory cytokines since apigenin and luteolin has been already identified as inhibitors of pro-inflammatory cytokine production in LPS-stimulated PBMC [ 32], and as factors which reduce the transcriptional activity of NF-κB in LPS-stimulated primary monocytes [ 33] and macrophages [ 34].
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The unique signature of the phytochemicals on this host of targets is explained parsimoniously by a common mechanism of action.
The significant differences for free radical scavenging activity among the different extracts may be attributed to the varied quantity of each of the phytochemical contents of the plant.
Agrimoniin and the luteolin and apigenin glycosides were identified as the main phytochemicals of AP.
The result of the phytochemical contents of Lenzites quercina extract (Table 2) revealed the presence of flavonoids, saponins, alkaloids, tannins, tepernoids and cardiac glycosides.
In this study, the antioxidative phytochemicals of Rhododendron oldhamii Maxim.
This suggests that most of the phytochemical constituents of B. oleracea leaves are polar and possess strong antioxidant potential.
A systematic mapping of the phytochemical composition of different SB fruits subspecies is still lacking.
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