Patients' continuation into subsequent phases of this study is dependent upon their response to their current treatment in the phase of study in which they are participating.
The phases of the study are shown in Fig. 1.
Figure 1 displays the accounting of the subjects through the phases of the study.
The phases of the study were done consecutively, each time approaching a new patient sample.
A four-week washout period was allowed between the phases of the study.
Statistical analysis was performed using the nonparametric Mann-Whitney test, after comparing the results of the 3 phases of study.
The findings, published in Monday's issue of Nature Medicine, come from the second of three phases of study required by the Food and Drug Administration for new drugs.
In the next phase of study, the team of engineers and planners will further winnow the options to about five based on ability to handle traffic, impact on the environment, cost and the demands of the community.
The first phase of Study 2 is the 8-week, double-blind, parallel-group, placebo-controlled Efficacy Phase.
Roche, the Swiss pharmaceutical company, is developing a good cholestoral drug that is scheduled to enter the final phase of study before approval, called phase three trials.
