The physiological effects of shift work may also influence drug activity and effectiveness, suggesting that persistent shift work may be incompatible with the efficacious treatment of disease.
In addition, the lesion produced a persistent shift of the body towards the side opposite to the lesion (Fig. 5D) as evidenced by the increased lateral shift angle from day 7 (6.4±2.1°) to day 60 post-lesion (5.2±8°) as compared to pre-lesion values (2.9±2.1°).
For the shortest washout intervals (Tables 1 and 2), however, the posterior channels demonstrate a persistent shift in the average center frequency suggesting a carry-over effect for these regions of the brain.
The retention of memory of recent results allows the CUSUM to detect even the small persistent shifts in rates which are otherwise easily missed.
Zhang, J., Tian, W., Chipperfield, M. P., Xie, F. & Huang, J. Persistent shift of the Arctic polar vortex towards the Eurasian continent in recent decades.
For a sustained increase of ligand concentration with time, the adaptive system generates a persistent shift of its activity from its adapted level, which suppresses the tumbling so that the bacterium can climb the gradient [10].
Importantly, during aging, a persistent shift from BAG1 to BAG3 determines the constitutive activation of the autophagic system for degradation of defective proteins.
No one argues that the change has been seismic or that these kind of films have come to dominate the mainstream, but just that there has been a persistent shift in that direction.
Overall, the ICM poll, carried out in mid-January, confirms a small but persistent shift in recent months towards remain, with 51% of those expressing a view saying they were now in favour of staying in the EU.
Indeed, they displayed either a slight and transient or a robust and persistent shift towards SS, denoting their subjective discounting of value attributed to the LL option.
