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No vesicles were observed in the outer nuclear layer compartment proximal to the outer limiting membrane (Fig. 2F).
At high magnification, pimonidazole staining in the outer retina was evident as linear processes extending through the outer nuclear layer and terminating at the outer limiting membrane.
The tissue was then dehydrated 2 minutes in each graded alcohol (2 times 95%, 2 times 100%), and defatted in xylene overnight to allow for better penetration across the outer limiting membrane of the retina.
Apart from the localization of PLEKHA7 in the outer limiting membrane of the retina, which contains heterotypic junctions between glial and neuronal cells, our observations suggest that the distribution of PLEKHA7 is essentially confined to epithelial junctions.
CRB1 encodes a transmembrane protein that is localized in Müller glial cells [17] at the subapical region (SAR) just above the adherens junctions (AJs) that form the outer limiting membrane (OLM).
In the retina, labeling was detected in the outer limiting membrane (OLM) (arrowhead in Fig. 2F), which has been previously shown to contain both AJ and TJ proteins [20], and along the junctions between retinal pigmented epithelial cells (arrow in Fig. 2F).
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· The judgments in the dossier went to the "outer limits", although not beyond the intelligence available.
Last year, 24-inch wheels seemed to mark the outer limits.
Well, almost, he was on the outer limit there.
Even this startling ratio is not the outer limit.
"We're at the outer limits of the possible right now," Mr. Vedrine said.
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CEO of Professional Science Editing for Scientists @ prosciediting.com