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All subjects were included in the outcomes analysis.
‡ Number of patients included for the outcomes analysis on ankle injuries.
Re-running the outcomes analysis without the open files had a trivial effect on model parameters.
A limitation for the outcomes analysis is that the monitoring tools have not been externally validated.
For NDSCR, 3.36% of cases for which outcomes were missing were excluded from the outcomes analysis only.
The analysis allows for dose comparisons between IRG or IRG clusters as defined in the outcomes analysis plan.
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A caveat of the outcome analysis for both studies could be the contribution of the medication withdrawal effect.
Three patients were not followed up for a minimum of 12 months and were therefore excluded from the outcome analysis.
Its graph-based architecture streamlines the outcome analysis and enables a straightforward way of including additional workflow extensions.
Those patients with whom we did not make telephone contact were excluded from the outcome analysis regardless of the information reported in their medical notes.
These data support the need for a future randomized trial, which should include an HRQOL measure as part of the outcome analysis.
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