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Greater statistical power can be achieved by expanding the outcome to include other frequently observed endpoints, such as unstable angina or the need for coronary revascularization (percutaneous coronary intervention or coronary artery bypass graft surgery).
In contrast, when we increased the specificity of the outcome to include the presence of both structural and functional renal impairment, the hazard ratio increased from 1.15 to 3.41 and was highly significant despite a dramatic reduction in the event rate (from 572 to 30).
Similar(58)
Some authors have sought to modify or adapt the BI from the original; these include reducing the number of items, 43 extending it with the addition of cognitive and social domains, 44 and attempts to further subdivide the outcomes to include different degrees of assistance.
The key secondary outcome expands the primary composite outcome to include time to first occurrence of hospitalization for unstable angina (4P-MACE).
We widened the definition of health outcome to include ability to impact health status as well as health status itself.
Second, we extended the model for each outcome to include all predictors that were significant at p < 0.10.
A second and quite different interpretation results if we expand the set of desires that determine the subjective utilities of outcomes to include the totality of the agent's preferences over time.
In the field of education, research has primarily focused on the role of social capital in children's academic performance; 5 6 however, subsequent research has expanded the range of outcomes to include health behaviours and population health outcomes.
Using this approach to assess falls, we defined the outcome measures to include the total fall rate and injurious fall rate.
The current study builds on the work of Schantz et al. (2001) by extending the outcome assessment to include affective state and olfactory function and the exposure assessment to include individual PCB congeners.
This study builds on the work of Schantz et al. (1999, 2001) and extends the outcome assessment to include domains such as affective state and olfactory function that they did not investigate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com