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Examination of the outcome code field found one procedure coded as 'death'death
Table 1 shows the outcome code definitions in AERS database.> CTCAE is a widely accepted, standard grading scale for adverse events throughout the oncology research community [ 14].
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We used the ISR field to identify the outcome codes of each AERS report.
Appendix 1 shows the outcome codes (international classification of diseases, ninth and 10th revisions).
We also sought to examine the association between spirometric test failure and a number of hiker characteristics, including age, sex, body mass index, respiratory health status, and respiratory health history using both stratified analyses and logistic regression modeling, where spirometric test failure was treated as the outcome (coded dichotomously as yes or no).
First, this study relies on administrative data only, and therefore some of the outcomes coded as an MI may not have been an MI, or those classified as transmural may have been miscoded as nontransmural, or vice versa.
In the model using this outcome coding, the odds ratios maintained their direction of effect, but only income and prenatal care adherence remained significant.
Inability to balance on one leg for five seconds was used as the outcome event (coded as 1) in logistic regression models.
SPSS version 22 was used to run multiple regression analyses (linear, binary logistic, and ordinal logistic) to determine how each possible variable impacted the global outcome codes of the transcripts.
We found that the AERS outcome codes used to record serious patient outcomes in the AERS reporting data correspond well to the CTCAE Grades 3 to 5. Semantic Web OWL rendering of the DDI-ADE dataset provides seamless integration with the CTCAE itself, enabling a standard infrastructure for automatic classification of ADEs based on the severity conditions specified in the CTCAE.
The rate of registry-retrieval linkage and correct assignment of outcome code improved over time.
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