structure-the organization of elements or parts in a complex system as dominated by the general character of the whole.
Key players in this network include proteins involved in focal adhesion of cell membranes to the extracellular matrix, the focal adhesion kinases [ 47], activators of the organization of cytoskeletal elements, the Rho GTPases, and cytoskeletal element organizing-proteins, actin and actin-associated proteins [ 43].
The organization of genetic elements which encode the originally identified HEPN domains and MNTs clearly resembles Type II TAs suggesting that these elements are novel TA systems [ 10] although their mode of action remained obscure.
The organization of these elements is very similar.
The genome itself could be viewed independent of additional data such as peptide-level data to gain insights into the organization of functional elements in these bacterial genomes.
As an example, ChIP-seq profiling of 13 transcription factors in embryonic stem (ES) cell development revealed the organization of regulatory elements into 'enhanceosomes' [ 21].
Curiously, as mentioned above, the vapE-containing region of GI1 is also duplicated in Xf strain 9a5c, as a part of GI5, resembling the organization of Vap elements in D. nodosus.
Moreover, regarding the organization of the elements that form the model of analysis of ethical conflict designed in this research, the results of the variance analysis for the variables "type of ethical conflict" and "IEEC" showed a statistically significant relation (p <0.05) between them for the 19 situations presented in ECNQ-CCV.
With regard to the organization of transcriptional regulatory elements, analysis of the human genome has revealed that distinct elements preferentially localize far upstream, at the promoter region, at the first intron, and at the 3′ region of genes.
