Exact(16)
To identify the optimal template structure for the loops/junctions, the model screens the pretabulated template library according to the loop size (first) and the sequence (second) matches.
The optimal template represents essential geological features of the training image, and its size is much smaller than the template size selected by entropy.
One of the challenging problems in designing templates is to find the optimal template that functions appropriately for the solution of the intended problem.
But contrary to our proposed method, their maximum margin temporal warping (MMTW) method relies on a costly SVM algorithm in order to extract the optimal template for the training dataset.
A simple threshold step is used at this stage as the third and final filter to determine the protein family, thus providing for selection of the optimal template molecule.
With the exception of the V6 region, the average candidate sequence found a template sequence that was between 3.7 and 7.5% different from the optimal template when using kmer searching; the V6 candidates averaged a difference of 12.5% from their optimal template.
Similar(44)
We assume that among available reference haplotypes, the optimal templates for imputing T are the descendants of the lineage with which T first coalesces.
The molecular structures of NEL domains from Yersinia pestis YopM (NCBI Reference Sequence: ZP_02316950.1) and Salmonella typhimurium SlrP (GenBank: AAD39928.1) were modeled using the described PCAIN methodology with the identified optimal template structure of Shigella type III effector IpaH (PDB ID: 3CKD).
Based on this, we introduce the correlation coefficient matrix to determine an optimal template, and the accuracy of template selection algorithm is also discussed.
Step two of the nested MSP was performed in a similar fashion with a few adjustments to the annealing temperature (60°C) to allow for optimal template discrimination, and to the PCR cycle number (25).
A few (100) of these were collected by hand and used to find an optimal template as described in the Sect. 3.
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