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Exact(5)
In addition, when the herniated lesion is migrated upward or downward behind the vertebral body, both approaches, and even anterior cervical discectomy and fusion, are impractical, and corpectomy is commonly considered as the only efficacious treatment.
Given that the currently available treatments to prevent HIV transmission and disease are not effective in eradicating the virus, vaccination likely represents the only efficacious adapted response to the global impact of this infection.
Previously, high dose interleukin-2 (HD IL-2) was essentially the only efficacious treatment of metastatic RCC (mRCC).
The potent artemisinin derivatives, combined with longer-half-life partner drugs, are the only efficacious treatments left for multidrug-resistant Plasmodium falciparum infection and thus form the cornerstone of antimalarial drug therapy.
The only efficacious prevention is an anti-tobacco campaign aimed at the general population, patients exposed to carcinogens, and patients treated for a previous lung or head and neck cancer (recommendation, expert agreement).
Similar(55)
If we assume that the cost to treat a patient in (where the treatment is not efficacious) is equal to the gain to treat a patient in S (where the treatment is efficacious), the utility assigned to the event that is rejected when the treatment is only efficacious in S, is given by.
For example, if a therapeutic intervention showed promise in one study but not another, a potential reason could be that the groups had significantly different mean peak VO2's and the therapy is only efficacious for those with adequate aerobic reserve.
We note that if copying were strongly biased so that individuals adopt effective treatments preferentially over ineffective ones, both acquisition and loss processes would favour effective remedies, leading to the spread of only efficacious treatments.
ADI-PEG20 is safe and the drug is only efficacious in melanoma patients whose tumour has negative ASS expression.
This is not surprising given the poor efficacy of SP. As a monotherapy, ART is usually taken for 7 days; a 3-day ACT course is only efficacious when the second drug retains adequate efficacy.
The other drug, eflornithine, is less toxic, though it is only efficacious for the gambiense subspecies and requires large amounts of drug which must be delivered by infusion over 14 days.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com