Exact(4)
This framework is then repeated by rotating the omitted study and assessing the validation in all the possible scenarios.
Only two articles used external validation (on different data), including a novel method which develops the model on all but one of the IPD studies, tests performance in the excluded study, and repeats by rotating the omitted study.
Where performance is consistently adequate across all combinations of the omitted study, a final step can be to utilise the IPD from all studies to produce the final specification of the model.
We will also apply leave-one-out approaches, as developed in the context of the modelling of prognosis of HIV infection [ 52], by fitting candidate models on pooled data from all but one of the studies and testing generalisability on the omitted study.
Similar(55)
Third, the omitted studies and subgroups will be analysed by sensitivity analysis.
In most of these omitted studies, the BMI range associated with the lowest mortality was around 22.5 25, particularly after accounting for smoking status and reverse causation due to prevalent diseases (Tobias & Hu, 2013).
By excluding studies lasting less than 3 days, the protocol omitted studies of post-prandial and 24 hr metabolism, except where these were investigated as part of a longer study (i.e., adapted individuals).
The authors deliberately omitted studies at mercury electrodes due to their claim that these electrodes were disappearing from laboratory benches and were generally unsuited for use in miniaturized and/or out-of-laboratory applications.
We also examined the effect of omitting studies with nested case-control design.
If relevant, the results of the methodological quality assessment will be used to perform sensitivity analyses to test the effect of omitting studies at high risk of bias.
Furthermore, the postcolonial pathway usually omits studies in American literature, thus forgoing any exploration into the wider relationships of African American writing to Africa, the Caribbean, and European diasporas, as well as an engagement with Latin American literature.
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