Sentence examples for the normal variant from inspiring English sources

Twenty-two patients with the condition, treated at six centers around the world, underwent so-called gene therapy, a process in which the normal variant of a gene is inserted into the patient's DNA, compensating for the abnormal one.

For the mammalian homolog we denote the normal variant gene and protein PRNP and PRNP (PrPC) respectively.

DNMT3L methylation percentage across all CpG sites analysed for cases with BRAF and KRAS mutation revealed increased methylation of the DNMT3L promoter in cases with a KRAS mutation when compared with polyps with the normal variant (p = 0.0053), however due to small number of cases this observation need to be investigated in a larger number of polyps harbouring KRAS mutation.

VarScan's default algorithm design returns somatic candidates if, for variant bases above 15 in quality, the cancer variant proportion is between 20 and 75% and the normal variant proportion is outside this range.

In addition to the normal variant, subtle glomerular abnormality and exaggerated hemodynamic response in the upright position as previously described, left renal vein entrapment has recently been shown to be related to orthostatic proteinuria [ 1, 4].

Both sequences viewed together facilitate the identification of normal MRI features and variants that may mimic SpA-associated inflammatory SIJ lesions on the semi-coronal plane alone [ 3], such as normal vascular structures mimicking BME or the normal variant of a bipartite ilium suggesting erosion by semi-coronal slices only [ 2].

"If it doesn't fundamentally mess up your work or social life, it's among the normal variants".

The functions safeexp and smoothstep are smoother versions of the normal variants of the exp and step function.

The normal variants on a margin have the potential to decrease the sensitivity and specificity of optical techniques for identifying malignancy.

Figure 3 shows the normal variants fibro-glandular (FG), fibro-adipose (FA), and adipose (A) in green, as well as the malignant variants (IDC in red and DCIS in black separated by disease depth).

The optical contrast for DCIS and IDC compared to the normal variants were similar with the exception of FG; DCIS showed differences from FG using [β-carotene] but none of the parameters separated IDC from FG.