Sentence examples for the next replication from inspiring English sources

Spontaneous deamination of 5-methylcytosine leads to a C to T transition via uracil formation and the replacement of thymine in one of the two daughter strands during the next replication round.

In cells deficient in MGMT, O-methylguanine is not repaired and results in the incorporation of a thymine (T) residue in the complementary position at the next replication cycle.

These gaps in the genome and double strand breaks (DSBs) that form at these sites during the next replication cycle have been proposed to be mediating the cytotoxic effects of different alkylating agents [ 8].

The basis for this statement is straightforward: if the enzyme binds too tightly to nonspecific DNA sequences, the residence time will be too long to efficiently scan the entire genome before the next replication event, while if interactions are too weak, insufficient time will be spent inspecting individual DNA base pairs, leading to overlooked base lesions.

H3K9me1 and H3K9me2 is diluted twofold upon DNA replication but is quickly restored during the G2 phase and is almost completely recovered before the next DNA replication.

DNA lesions become mutagenic if they persist until the next DNA replication round.

It was reported that the sticky end formed by this TNT activity is favourable for the next round replication of the dsRNA [ 17].

Replication of the unremoved adduct leads to a DSB in the next round of replication.

During replication, uracil pairs with adenine resulting in a C G->T A transitions in the next round of repliC G->T A

In the present study, we showed that selenite arrested NB4 cells at G0/G1 phase by inhibiting the expression of cyclin D1, cyclin D3, CDK 4 and cyclin A. Cells at the G0/G1 checkpoint are surveyed to determine whether their DNA replicates correctly, and these cells will not transition to the next phase until replication problems are solved.

Secondly, the DNA mismatch repair (MMR) system recognizes and corrects the remaining errors that arise during replication and also repairs several forms of DNA damage, thereby preventing the manifestation of mutations in the next round of replication.