The measurement is of considerable importance in the presence of suspected stenosis not detectable in the supine position, with the necessary considerations resulting from the therapeutic point of view.
The last section describes the bridging of biomarkers from preclinical laboratory studies into the clinical realm, and the necessary considerations in terms of technical validation of biomarker endpoints, the role of biomarkers as surrogate endpoints and in pharmacokinetic/pharmacodynamic modeling, and how biomarkers may be viewed in a regulatory context.
This chapter provides an understanding of the basic approach to the successful management of water in a modern food processing operation, based around legislative and economic criteria, but encompassing the necessary considerations for site and corporate managers, especially with regard to engineering.
In this paper we will outline the necessary considerations for implementing diagnostic radiology services in resource-poor settings, discuss modality options for both X-ray and ultrasound, and argue that it is both necessary and feasible to rapidly scale up these technologies.
The example of crizotinib's accelerated approval featured prominently throughout this presentation and others as a way to highlight the potential of larger treatment effects to allow for smaller trials; the role of the companion diagnostic as a necessary consideration in developing targeted therapy studies; and the time and cost savings of focused trials in appropriately selected patients.
A necessary consideration, given the acoustic differences between the played set and the claim and shape sets at onset closure, is to determine whether the increased activity for linguistically complex words observed at both sensor and source levels might be related to low-level acoustic differences in our stimuli.
The neoclassical economic model of a person is called Homo economicus, describing a person who "interacts in society without being influenced by society," because "his mode of interaction is through an ideal market," in which prices are the only necessary considerations.
I'm not saying that protection of the public isn't a necessary consideration for any criminal justice agency, or indeed that the probation service does not still undertake valuable rehabilitative work.
In both contexts the spectrum and frequency of gene variation in the general population is a necessary consideration when evaluating potential association with disease.
