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Rousseeuw and Leroy (1987) indicate that robust estimation procedures are essential to identify the most reliable sample of the dataset and these can help identify possible outliers in the estimation model.
In the case wherein a gene is represented by more than one probe-set on the array, a single probe-set was chosen to represent gene expression in the heat map according to highest mean expression over all samples (i.e. the most reliable sample hybridization regardless of group membership).
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This study was undertaken to establish one of the most reliable sampling methods and to precisely evaluate the bias involved in the collection of airborne pollutant samples.
A comprehensive experimental study is conducted and statistically analyzed to detect the most reliable sampling strategy to be used as the PMP engine of the loop.
The EST data likely provides the most reliable sampling of the true protein coding regions in these genomes, since it is based on experimental data that contain species-specific sequences not available in the protein database.
According to the authors, however, the most reliable blood sample for S100A12 determinations would be serum stored in gel-containing tubes, as in our study [ 32].
Viremia is not evident in PRV-infected pigs (19 ), and our results showed that PRV was found at a considerably higher rate in brain tissue than in blood; thus, brain tissue is likely to be the most reliable clinical sample for diagnosing PRV infection.
Despite these potential confounders we found that the score tool functioned equally well on biceps and quadriceps tissue, and the same score items were the most reliable for both sample sets.
The most reliable method of probability sampling, known as random sampling, requires that each member of the universe have an equal chance of being selected.
The corresponding number of validated reference genes will approach the most reliable NF calculation across sample leading to accurate data normalization.
Guidelines suggest that an in-and-out catheter may be the most reliable way of obtaining a urine sample in the female population if a voided sample cannot be obtained.
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