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Making glass stronger is perhaps the most difficult problem, and potentially the most astonishing advance.
And where do you go from here? A. It was the most difficult problem.
By far the most difficult problem is the future of America's military role in Asia.
"I am a natural choice to solve the most difficult problem facing the city now, education and its fiscal instability".
"My brother-problem", he wrote in a letter in 1917, "is the real, in any case the most difficult, problem of my life..
And that is "the most difficult problem that Fox will face" when he takes office on Dec. 1, said a senior diplomat in Mexico City.
He said he thought he had already identified the most difficult problem he would have adjusting to life in New York after decades in Omaha and Washington.
His methods for isolating cause-and-effect relationships -- arguably the most difficult problem in applied economics -- have also won him wide admiration in his field.
The most difficult problem Ootala has on his desk is the shortage of doctors in rural areas like Katine, where there is no doctor working at the clinic.
As part of their conversations with Afghan women, the Marines are to ask basic questions, including what is the most difficult problem facing the village.
"Many, many community college presidents will say that math developmental education is the most difficult problem they're facing," Dr. Bailey said.
More suggestions(12)
the most troublesome problem
the most difficult predicament
the most serious problem
the most difficult issue
the most knotty problem
the most delicate problem
the most awkward problem
the most difficult challenges
the most difficult challenging
the most difficult problematic
the most difficult subjects
the most common problem
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com