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The Morph is a fun little computer peripheral.
In a sense, the Morph is as much a way of proving that Sensel's technology truly works.
The Morph is starting out with three overlays that hook in via magnets: a keyboard, an MPC-style MIDI controller, and a piano/drum pad.
The Morph is up for pre-order on Kickstarter now with an early-bird price of $199, which bumps up to $249 as soon as early-bird runs out.
The change in frequency of the morph is almost certainly the result of a strong selective pressure, initially positive and changing direction some time in the mid 20th century.
The Ramachandran plot of phi versus psi angles of the intermediate structure, which occurs halfway through the morph, is shown in Figure 2. The majority of the points in the plot fall within a region that is observed in real proteins.
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The morph was created by interpolating between T, Rs1, Rs2 Rs-open, and R-ES conformations.
We plot the RMSD of our intermediate structures against each of these four proteins in Figure 3. Intermediates which are produced early in the morph are closest to the starting protein, 1DY3, while those that are produced late in the morph are closest to the ending protein, 1RAO, as expected.
As commented before, the morphing is automatic: we start from two images I1 and I2 to which the multiGaussian mixture energy function segmentation method is applied.
The process ends when the target molecule is located; namely, when one of the morphs is identical with the M T. The sequence of morphs from M S to M T defines the path in chemical space.
In some species, one of the morphs is very rare (such as brown morphs in Decticus verrucivorus), while in others the ratios are far more even (as in Metrioptera roeselii) [ 14].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com