Sentence examples for the modification states from inspiring English sources
RNA molecules, such as long noncoding RNAs (lncRNAs), have critical roles in regulating gene expression, chromosome architecture, and the modification states of chromatin.
Detection of these variants suggests a difference exists in the modification states of these tRNAs for the sample analyzed as compared to those already catalogued in the modified tRNA databases.
Furthermore, when we compared the modification states of H3K9 and H3K14 depending on the modification state of H3S10, we observed that the H3K9 and H3K14 modification patterns differed based on the phosphorylation state of H3S10.
Many studies have revealed that the modification states of the histones are not evenly distributed among all possible states but rather reflect correlations of the modified forms of specific residues, yet there is an absence of biochemical studies that provide mechanisms that clearly account for the generation of only a small subset of the possible states.
The modification state of each of these residues was analyzed by mass spectrometry, and nine out of the ten proline residues were found to be hydroxylated (Fig. 7E)- the lone exception was Pro-123.
Recruitment of de novo methyltransferases has been shown to depend on the modification state of the associated histones.
The upper or β-axial ligand varies, depending on the modification state of cobalamin (R-group in Fig. 1a).
In addition, DNA de novo methylation can occur with probability Dnovo > 0 depending on the modification state of the associated nucleosomes.
The actual transcriptional and biological outcome of Smad activation critically depends on the genomic integrity and the modification state of genome and chromatin of the cell.
The most commonly studied examples are from PTM recognition domains that are also known as 'reader' domains for their capacity to read the modification state of a protein.
The second file contains biochemical data relating to the changes in the modification state (typically phosphorylation) of proteins following stimulation under various conditions.
