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Although preliminary due to the modest sample size, the findings encourage a larger scale investigation with greater statistical power to evaluate competing models of genetic influence.
However, due to the modest sample size, further assessment of MPO and TnI is needed.
This may be due to the modest sample size and/or because T2D cases and NGT controls were not specifically selected from families with or without history of diabetes, respectively, and/or because T2D cases and NGT controls were not matched for BMI.
While this lack of association may be due to the modest sample size or hidden biases such as population stratification, it may also signify that other SNPs in the same genes or located in different genes could be associated in the North African population.
The modest sample size may be interpreted as a limitation.
Our results are limited by the modest sample size.
It is worth noting moreover that, given the modest sample size, some subgroups were relatively small.
The modest sample size is also a limitation which further studies can improve upon.
The modest sample size may have lacked power to detect statistically significant interactions.
The modest sample size and single-center study design could affect the generalizability of the results.
Besides the modest sample size, the other major limitation was the absence of a sham condition.
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