XQ cleaned the data, participated in the discussion of the analytic framework, operationalized the analytic models, tested the models, drafted the manuscript, and revised the drafts.
TC designed and built the models, drafted parts of the manuscript and the figures.
Both authors took part of the modeling, drafted, read, and approved the final manuscript.
WK performed the spatial analysis, produced the map, conceptual model, drafted the article, and conducted the literature review.
Thus, some reactions may be not included in the model draft.
The model draft of the designated microorganisms, automatically generated from the KEGG database, should be reconstructed to fill in the gaps between the genome annotation and the functional metabolism.
WK undertook the spatial analysis, produced the map and conceptual model, drafted the paper and carried out the literature review.
VR undertook the multilevel modelling, drafted the methods and results sections, contributed to the interpretation of the results and commented on successive drafts of the manuscript.
SK carried out numerical modeling, drafted the manuscript, and obtained permission for the field survey.
DWH designed the study, managed and analyzed the data, created the model, and drafted the manuscript.
