The mean intensity of spots containing buffer only was calculated for each row of sub-grids, and was taken as the minimum intensity of probes for that subgrid.
0 indicates the minimum intensity of that component, while 255 indicates the maximum intensity.
We measured the minimum intensity required for eliciting an H-reflex of 0.2 mV (H-threshold), the amplitude and latency of the H-reflex at MTh and the amplitude of the H-reflex and M-wave at 1.5 MTh.
The minimum intensity threshold for MS/MS fragmentation in the Orbitrap analyzer was 5000 counts and the dynamic exclusion was set to 60 sec with repeat count as one.
For the resulted structure the minimum intensity contrast ratio for OR and NOR gate obtained to be 25 dB and 19.8 dB respectively.
Images were ultimately generated by setting for each considered m/z value the minimum intensity at 5% and the full intensity threshold at 100%.
The same procedure was applied for the sensory threshold, which was defined as the minimum intensity needed to just notice the stimulation impulse.
The normalization process need the maximum and minimum intensity for each pixel which can be calculated as: {I}_{mathrm{min}}left x,yright)=Aleft x,yright -Bleft x,yright -Bleft x}_{mathrm{max}}left(x,yright)=Aleft(x,yright)+Bleft(x,yright) (24).
