Often, the materials are expensive, the methods are time consuming, and the production processes can generate toxic hazards.
The methods are time consuming, tedious, and prone to subjectivity.
However, the method is time consuming, and it is not always effective.
The method is time consuming, expensive, and often leads to misinterpretation of results when interactions between different components are present.
The method is time consuming and due to its complexity sometimes it fails to optimize the reactant complex at a transition state level.
However, the method is time consuming and personnel-intensive [ 3].
Other limitations, such as the fact that the method is time consuming and the results are influenced by various factors (e.g., temperature and needed culture time), have been well discussed previously [ 5, 11– 11].
The visual description of individual's pain patterns was a pragmatic and clinically meaningful way to distinguish between obviously different patient profiles, but the method is time consuming and only doable in small samples.
Furthermore, the clinical use of thromboelastometry variables as a biomarker for severe sepsis might be limited by the fact that citrated whole-blood samples have to be processed within a short time frame, and that the method is time consuming when compared with automated laboratory methods.
With the exception of ICP-MS, these methods are time consuming, often expensive, and therefore not convenient when large number of samples are to be analyzed.
