However, compared to the methods previously mentioned, this method requires: (i) the optimization of more parameters, therefore limiting the scalability, and (ii) the availability of detailed time resolved data.
The crude extracts were extracted using the same method previously mentioned, except for the addition of potassium phosphate buffer instead of MOPS buffer.
We show that its performance at the highly linked regions is no worse than the best method previously mentioned.
Previous publications evaluating different viral systems for gene transfer in primary human monocyte-derived macrophages used the three methods previously mentioned to induce cell differentiation: HS, M-CSF and GM-CSF [ 13, 30, 31].
The processing algorithm converts raw data to an image which includes the Fourier transform of data with FFTW [ 22] with interpolation methods previously mentioned, numerical dispersion compensation [ 23], logarithmic scale calculation, contrast and brightness adjustment as well as on screen display.
We also determined three post hoc composite outcomes: (a) if indicated, using anesthesia and pain control, and stating the method of euthanasia; (b) the previously mentioned criteria, and in addition that, if stated, the method of euthanasia was appropriate for the species; and (c) the aforementioned criteria, and in addition that a sample-size calculation was provided in the publication.
In this section, the application of the previously mentioned methods for finding different dynamically equivalent structures will be illustrated using biological models taken from the literature.
(2007) applied this method to the previously mentioned data set of brain gene expression and unveiled two anticorrelated modules containing cell proliferation‐ and cell differentiation‐related proteins.
(2008) applied this method to the previously mentioned gene expression data set of 30 human frontal cortex samples at different ages and then compared the results with a network derived from an AD transcriptomics study.
Here, the AIP were markedly higher than most of the AIJ, also in comparison with the AIPs of the previously mentioned aggregation methods.
Note that the application of the previously mentioned generic methods on an arbitrary system as the one we consider would also require to solve a linear system or an eigenproblem.
