(2) On page 3, the fact that the sequence ( c n ) n ∈ N is bounded follows now from the above mentioned hypothesis, using the following remark: by 3., for each x ∈ Y, we have that d ( x, f n ( x ) ) < + ∞ for all n ∈ N ∗.
This strengthens the above mentioned hypothesis that the intensity fluctuations are caused only by changes that affect the interface between inner and outer segments of cone photoreceptors.
It is important here to bear in mind the previously mentioned hypothesis that the type 2 patient phenotype could be particularly important, since the expression of alternative RAGE splicing could be genetically determined, featuring a different susceptibility to glycoxidation.
The previously mentioned hypothesis would also suggest that the low diagnostic rate in this study might be related to the etiology of the bleeding itself, which was most frequently found to be erosions and ulcers.
Also, men comprised 40% of the present study population, but they account for 30% of the general GEMIDAS (years 2002 to 2008) population, supporting the previously mentioned hypothesis of a more generous prescription in men.
This finding may thus seem to corroborate the above mentioned hypothesis that stigma does not actually play a role in the dynamics of the HIV epidemics.
In order to test the above mentioned hypothesis fully objectively an individual patient data meta-analysis of the RCTs must be conducted, which would ideally use comprehensive patient level data to allow for more statistically robust time-to-event analyses and also identification of possible sub-groups with increased risk of MACEs.
However, the use of pacifiers has been described as having a protective effect against Sudden Infant Death Syndrome [2, 3], but the level of evidence is very low [9], since no RCTs are available that has reliably tested the above mentioned hypothesis [11].
