Parallel to data on HIF-1α, β-secretase inhibitor treatment re-established HIPK2 recruitment onto MT2A promoter thus counteracting the APP-conditioned medium ability to affect HIPK2 binding to DNA (Figure 2b, right panel).
In agreement with our hypothesis, β-secretase inhibitor treatment counteracted the APP-conditioned medium ability to inhibit HIPK2 binding to DNA and re-established HIPK2 recruitment onto HIF-1α promoter (Figure 2a, right panel).
However, VR's unique and unprecedented power, lies not in its ability to remove the human from this society, but rather in the medium's ability to immerse the user ever deeper into it.
And the only serious factual show to figure is Frozen Planet which, given that Sir David Attenborough is 85, raises concerns about the medium's ability to renew itself.
The weakness of television directors is the strength of the medium — its ability to become the very source of discourse.
The Brücke artists helped to revive the woodcut tradition in Germany; they prized the medium's ability to convey rough, spontaneous marks and bold, flat colour.
Because of the medium's ability to preserve the stages of decision-making on separate sheets and because of the distinctive look of different techniques combined to bracingly dissonant effect, it exposes the artist's process with particular lucidity.
Mr. Mikitani contends that Japan will be a better market for e-commerce than the United States, mostly because of the medium's ability to spark a consumer revolution in a country known for its high prices.
When the model Chrissy Teigen joined Twitter, in 2009, she revealed her love for sausage-and-egg McMuffins, Pizza Hut, and tater tots, and the medium's ability to portray a real-time inner monologue.
These enchanting photo sequences and montages, which are often accompanied by Michals's handwritten prose, make innovative use of the medium's ability to suggest what cannot be seen.
