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When PLR induced the maximal effect on the stroke volume, hemodynamic measurements were recorded again.
The maximal effect has been revealed for the sample exposure time of 3 min (curve 3).
The maximal effect was obtained at a 25-μM concentration which is similar to concentrations of PPF used clinically.
The use of non-depolarizing muscle relaxants in these patients is associated with an increase in the maximal effect and duration of action [1].
Thus, the effect of intravenous olcegepant 2.5 mg is most likely near the maximal effect one can expect of a CGRP antagonist in migraine.
In the studies involving normal healthy subjects, 10 mg furosemide produced diuresis and 40 mg intravenously administered was associated with the maximal effect.
Compounds were washed out once the maximal effect was observed.
Vmax is the maximal effect of the chemical over the concentration range.
V0 is the feeding level at the concentration producing the maximal effect.
For these cells, the maximal effect (80%) was achieved at 1 mM of BP7033Br.
The maximal effect of Boc5 was similar to that of exenatide observed in the same experimental protocol.
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