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Biomarkers are actively sought for the majority of diseases associated with major societal and economic burden in developed countries (e.g. dementia, renal and cardiovascular disease, and most malignancies).
Some plants can only enter Britain with "passports", but the majority of diseases are only identifiable in laboratories.
Patients ask me, "Do you take care of men too?" I may be partly to blame for the confusion: in the years since the revolutionary 1985 report on women's health from the United States Public Health Service, I — along with many of my colleagues — have tried to atone for the fact that for so long the majority of diseases that afflicted both genders were studied exclusively in men.
As proteins are found in the majority of diseases we suffer from, they are also key to developing cures, and so FoldIt enables gamers to design new proteins and fold known proteins into their most workable forms in an effort to contribute to disease prevention.
Thus, we could reject a model for the genetic architecture of type 2 diabetes where rare nonsynonymous variants clustered in a modest number of genes (fewer than 20) are responsible for the majority of disease risk.
However the majority of disease-associated mutations cause missense single amino acid substitutions.
These diseases account for the majority of disease burden, and the majority of health care cost, globally.
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