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Because the mainstream method of searching for candidate SNP markers is now based on a statistical estimate of the similarity between the projections of unannotated SNPs and known SNP markers on various genome-wide maps, here we simplified the procedure by limiting it to unannotated SNPs only that are located near the known SNP markers in the TBP-binding sites of human genes.
Full-length cDNA sequences will even be valuable in transcriptome analysis with NGS, which will become the mainstream method of expression analysis; these sequences will be useful in determining which short NGS reads belong to gene sequences that truly exert functions in organisms [ 16].
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Nowadays, deployment of autonomous mobile vehicles or platforms has become the mainstream method in ocean observation.
Thus, the single-locus approach is still the mainstream method in GWAS.
In this chapter, we discuss design optimization one of the mainstream methods in support of engineering design.
And as cryptos, at least the top few, become more mainstream method of personal investment and a rising payment method for goods and services around the globe, traditional financial institutions are scrambling.
Hand gestures will become a mainstream method of manipulating human computer interfaces (HCIs).
Indeed, once considered gadgets, digital cameras are becoming accepted as mainstream method of capturing memories.
Medical simulation is becoming a mainstream method of medical education [ 4- 8] and evaluation[ 9, 10].
Observing differential expressions of one or more genes between normal and abnormal cells has been a mainstream method of discovering pertinent genes in diseases and therefore valuable drug targets.
Most of the existing approaches rely on statistical models [6, 7], and the approach based on the Gaussian mixture model (GMM) [8 11] is one of the mainstream methods used nowadays.
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